Neuro-Ophthalmology: From Bench to Bedside, and Back

Início:

18 Setembro, 2025

Fim:

20 Setembro, 2025

Local:

Lisboa - Fundação Champalimaud

Fundação Champalimaud, Avenida Brasília, Lisboa, Portugal

Entidade Organizadora / Responsabilidade Científica
Drs. David Zee, Alex Tarnutzer, Alessandra Rufa, Aasef Shaik, Caroline Froment Tilikete

Temas principais
Neuropatias Ópticas, Movimentos Oculares, Campimetria, PEV, OCT, Estrabismo

18-20 September 2025

DAY 1 (18 SEPTEMBER)

40 minutes per talk, three talks per session (C1, C2, C3, C4). Total of 4 sessions

Session C1

  • Dave Zee’s SRCA talk (Fernando Rossi lecture)
  • Integrative network models in dystonias – lessons learned from eye movements and applied to movement disorders
  • Computational models of eye movements (?)

Session C2

  • Visually guided behaviour
  • Control of complex behavior by the cerebellum
  • Gaze and Posture

Session C3

  • Talk TBD
  • Talk TBD
  • Gene therapy for retinal diseases

Session C4

  • Talk TBD
  • Mathematical models of peripheral positional nystagmus (?)
  • Mathematical models of central positional nystagmus

DAY 2 (19 SEPTEMBER)

Each session has 3 talks, one scientific or basic science talk and two translational or clinical, and one case presentation

Duration of talks: 30min
Duration of case presentation: 20 minutes including discussion (10-minute panel discussion)

Session C1

  • Tips, tricks and pearls to diagnose eye movement disorders
  • Approach to jerk nystagmus
  • Approach to pendular nystagmus
  • Case Presentation

Session C2

  • High level view of computational modeling in clinical neurology
  • Membrane based models of disorders of saccades and gaze-holding – implication in autoimmune disorders (?) (we need a clinical talk here)
  • Saccades and saccadic intrusions in neurodegenerative disorders
  • Case Presentation

Session C3

  • High level view of machine learning and artificial intelligence and BigData in genetics of neurological disorders
  • Hereditary ataxias
  • Hereditary optic neuropathies
  • Case Presentation

Session C4

  • Computational modeling of ocular motor plant (?)
  • Approach to strabismus
  • Eye movements in myasthenia and related disorders
  • Case Presentation

DAY 3 (20 SEPTEMBER)

Session C5

  • What do the eye movements teach us about fatigue in multiple sclerosis
  • Afferent visual function in multiple sclerosis
  • The optic nerve in neuromyelitis optical spectrum disorders/MOGAD
  • Case Presentation

Session C6

  • Artificial intelligence in fundus photography
  • Ischemic optic neuropathy
  • Differential diagnosis of disc edema: intracranial hypertension and more
  • Case Presentation

Session C7

  • Migraine and visual phenomena: lessons learned from structural and functional imaging
  • How to interpret visual fields
  • Pupils in neuro-ophthalmology
  • Case Presentation

Session C8

  • Retinal imaging in animal models: Searching for biomarkers of neurodegeneration
  • The clinical use of optical coherence tomography in assessing retrograde degeneration in post-chiasmal, chiasmal, and pre-chiasmal disease
  • How to interpret visually evoked potentials
  • Case Presentation